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Glee Season1-Sectionals

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Glee Season 1: Sectionals

Is Quinn's baby at risk for Tay-Sachs?

Rachel gets it all wrong.




YouTube Video Link is:

http://www.youtube.com/watch?v=nL9Dxf3B8Sk

Description:
rachaeliification | November 10, 2010

Source: http://www.projectshui.com/Glee_Quinn...

In this clip from Glee, Episode 1 "Sectionals", Rachel is mischievously trying to figure out if Puck, who is Jewish, is the father of Quinn's baby. She asks Quinn if she's been tested for Tay-Sachs and incorrectly informs her that only Jews carry the gene for Tay-Sachs. Her ploy works and Rachel figures out that Puck is in fact the father. However, in the process, Rachel unfortunately misinforms the viewers about Tay-Sachs.

Ashkenazi Jews do have an increased carrier rate for Tay-Sachs of 1: 27 (One in every 27 Ashkenazi Jews is a carrier for the gene), but so do French Canadians and Lousiana Cajuns. 1 in 50 Irish Americans is a carrier, which is also very high. In the general population, 1 in 250 people is a carrier for the gene.

Given that Quinn is an Irish name, it is possible, if she is from Irish decent, that Quinn is the one at increased risk for Tay-Sachs (1 in 50 chance). While Puck, who appears to have more of a Sephardic Jewish look (as opposed to Ashenazi Jewish), could have the much lower 'general population' risk of 1 in 250.

Either way, given the possible combined heritage of Irish and Jewish, Quinn's baby has a Significantly Higher risk of having Tay-Sachs than the average baby. If one parent is a carrier, the baby has a 50% chance of being an unaffected carrier. If both parents are carriers, the baby has a 25% chance of having Tay-Sachs disease.

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